Dr. Sandhya S. Visweswariah
| Grant Category: | Fulbright-Nehru Senior Research Scholar |
| Field of Specialization: | Biochemistry; Cell Biology |
| Name: | Dr. Sandhya S. Visweswariah |
| Official Address and Designation: | Professor Department of Molecular Reproduction, Development and Genetics Indian Institute of Science Bangalore 560 012 Karnataka |
| Telephone (O): | 91-80-22932542/23601522 |
| E-mail: | sandhya@mrdg.iisc.ernet.in |
| Duration of Grant: | Six Months |
| Project Title: | The importance of cyclic nucleotide signaling in the biology and pathogenesis of M. tuberculosis |
| Abstract of Project : | |
| Most of the proteins involved in cyclic AMP metabolism in mycobacteria were described for the first time in the Visweswariah laboratory, and their characterization has revealed their unique properties. The research in the U.S. will examine the roles of the enzymes in the biology of mycobacteria by creating gene knock outs of these proteins in Mycobacterium tuberculosis, and stud the properties of these mutant bacteria in the mouse model of infection as well as in macrophages. Should the bacteria be compromised in their pathogenic potential, some of the proteins could be the targets of novel therapeutics for treatment of tuberculosis. | |
| Academic Background : | |||
| Ph.D. | Biochemistry | Indian Institute of Science, Bengaluru | 1987 |
| M.Sc. | Chemistry | IIT Kanpur | 1980 |
| B.Sc. | Botany, Chemistry, Zoology | Osmania University, Hyderabad | 1977 |
| Professional Background : | |||
| Professor | Indian Institute of Science, Bengaluru | 2005-till date | |
| Associate Professor | Indian Institute of Science, Bengaluru | 1999-2005 | |
| Assistant Professor | Indian Institute of Science, Bengaluru | 1993-1999 | |
| Scientist | AstraZeneca, Bengaluru | 1987-1993 | |
